• Peer reviewed contributions
• Book chapters
• Patents
• Conference contributions

Peer reviewed contributions

1. S. Geissbuehler, A. Sharipov, A. Godinat, N. L. Bocchio, P. A. Sandoz, A. Huss, N. A. Jensen, S. Jakobs, J. Enderlein, F. G. van der Goot, E. A. Dubikovskaya, T. Lasser, M. Leutenegger
   Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging
   Nature Commun. 5: 5830 (2014)
2. S. Broillet, D. Szlag, A. Bouwens, L. Maurizi, H. Hofmann, T. Lasser, M. Leutenegger
   Visible light optical coherence correlation spectroscopy
   Opt. Express 22: 21944-21957 (2014)
3. S. J. Sahl, M. Leutenegger, S. W. Hell, C. Eggeling
   High-Resolution Tracking of Single-Molecule Diffusion in Membranes by Confocalized and Spatially Differentiated Fluorescence Photon Stream Recording
   ChemPhysChem 15: 771-783 (2014)
4. S. Broillet, A. Sato, S. Geissbuehler, C. Pache, A. Bouwens, T. Lasser, M. Leutenegger
   Optical Coherence Correlation Spectroscopy (OCCS)
   Opt. Express 22: 782-802 (2014)
5. S. R. Krishnan, C. S. Seelamantula, A. Bouwens, M. Leutenegger, T. Lasser
   Zero-crossing approach to high-resolution reconstruction in frequency-domain optical-coherence tomography
   J. Opt. Soc. Am. A 29: 2080-2091 (2012)
6. S. Geissbuehler, N. L. Bocchio, C. Dellagiacoma, C. Berclaz, M. Leutenegger, T. Lasser
   Mapping molecular statistics with balanced super-resolution optical fluctuation imaging (bSOFI)
   Opt. Nanoscopy 1:4 (2012)
7. M. Geissbuehler, L. Bonacina, V. Shcheslavskiy, N. L. Bocchio, S. Geissbuehler, M. Leutenegger, I. Märki, J.P. Wolf, T. Lasser
   Nonlinear Correlation Spectroscopy (NLCS)
   Nano Lett. 12, 1668-1672 (2012)
8. M. Leutenegger, C. Ringemann, T. Lasser, S. W. Hell, C. Eggeling
   Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS)
   Opt. Express 20, 5243-5263 (2012)
9. V. Mueller, C. Ringemann, A. Honigmann, G. Schwarzmann, R. Medda, M. Leutenegger, S. Polyakova, V. N. Belov, S. W. Hell, C. Eggeling
   STED Nanoscopy Reveals Molecular Details of Cholesterol- and Cytoskeleton-Modulated Lipid Interactions in Living Cells
   Biophys. J. 101, 1651-1660 (2011)
10. T. Grotjohann, I. Testa, M. Leutenegger, H. Bock, N. T. Urban, F. Lavoie-Cardinal, K. I. Willig, C. Eggeling, S. Jakobs, S. W. Hell
    Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
    Nature 478, 204-208 (2011)
11. T. Brakemann, A. C. Stiel, G. Weber, M. Andresen, I. Testa, T. Grotjohann, M. Leutenegger, U. Plessmann, H. Urlaub, C. Eggeling, M. C. Wahl, S. W. Hell, S. Jakobs
    A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching
    Nature Biotechnol. 29, 942-947 (2011)
12. M. Leutenegger, E. Martin-Williams, P. Harbi, T. Thacher, W. Raffoul, M. André, A. Lopez, P. Lasser, T. Lasser
    Real-time full field laser Doppler imaging
    Biomed. Opt. Express 2, 1470-1477 (2011)
13. M. Leutenegger, C. Eggeling, S. W. Hell
    Analytical description of STED microscopy performance
    Opt. Express 18, 26417-26429 (2010)
14. K. Kolmakov, V. N. Belov, C. A. Wurm, B. Harke, M. Leutenegger, C. Eggeling, S. W. Hell
    A Versatile Route to Red-Emitting Carbopyronine Dyes for Optical Microscopy and Nanoscopy
    Eur. J. Org. Chem. 2010, 3593-3610 (2010)
15. S. J. Sahl, M. Leutenegger, M. Hilbert, S. W. Hell, C. Eggeling
    Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids
    Proc. Nat. Ac. Sci. 107, 6829-6834 (Apr 2010)
16. M. Geissbuehler, T. Spielmann, A. Formey, I. Märki, M. Leutenegger, B. Hinz, K. Johnsson, D. Van De Ville, T. Lasser
    Triplet Imaging of Oxygen Consumption during the Contraction of a Single Smooth Muscle Cell (A7r5)
    Biophys. J. 98, 339-349 (2010)
17. C. Ringemann, B. Harke, C. von Middendorff, R. Medda, A. Honigmann, R. Wagner, M. Leutenegger, A. Schönle, S. W. Hell, C. Eggeling
    Exploring single-molecule dynamics with fluorescence nanoscopy
    New J. Phys. 11, 103054 (2009)
18. D. Ivanov, V. Shcheslavskiy, I. Märki, M. Leutenegger, T. Lasser
    High volume confinement in two-photon total-internal-reflection fluorescence correlation spectroscopy
    Appl. Phys. Lett. 94, 083902 (2009)
19. A. Raabe, D. Van De Ville, M. Leutenegger, A. Szelényi, E. Hattingen, R. Gerlach, V. Seifert, C. Hauger, A. Lopez, R. A. Leitgeb, M. Unser, E. J. Martin-Williams, T. Lasser
    Laser Doppler imaging for intraoperative human brain mapping
    NeuroImage 44, 1284-1289 (2009)
20. M. Leutenegger, T. Lasser, E.K. Sinner, R. Robelek
    Imaging of G protein-coupled receptors in solid-supported planar lipid membranes
    Biointerphases 3, FA136-FA145 (2008)
21. M. Leutenegger, T. Lasser
    Detection efficiency in total internal reflection fluorescence microscopy
    Opt. Express 16, 8519-8531 (2008)
22. R. Robelek, M. Leutenegger, B. Wiltschi, E. S. Lemke, D. Oesterhelt, T. Lasser, E. K. Sinner
    In vitro synthesis of GPCRs in a solid supported planar lipid membrane system
    Biophys. J., 38A Suppl. S (2007)
23. M. Leutenegger, R. Rao, R. A. Leitgeb, T. Lasser
    Fast focus field calculations
    Opt. Express 14, 11277-11291 (2006)
24. M. Leutenegger, H. Blom, J. Widengren, C. Eggeling, M. Gösch, R. A. Leitgeb, T. Lasser
    Dual-color Total Internal Reflection Fluorescence cross-Correlation Spectroscopy
    J. Biomed. Opt. 11, 040502 (2006)
25. L. C. Hwang, M. Leutenegger, M. Gösch, T. Lasser, P. Rigler, W. Meier, T. Wohland
    Prism-based multicolor fluorescence correlation spectrometer
    Opt. Lett. 31, 1310-1312 (2006)
26. M. Leutenegger, M. Gösch, A. Perentes, P. Hoffmann, O. J.F. Martin, T. Lasser
    Confining the sampling volume for FCS using a sub-wavelength sized aperture
    Opt. Express 14, 956-969 (2006)
27. K. Hassler, M. Leutenegger, P. Rigler, R. Rao, R. Rigler, M. Gösch, T. Lasser
    Total internal reflection fluorescence correlation spectroscopy (TIR-FCS) with low background and high count-rate per molecule
    Opt. Express 13, 7415-7423 (2005)
28. B. Karamata, P. Lambelet, M. Laubscher, M. Leutenegger, S. Bourquin, T. Lasser
    Multiple scattering in optical coherence tomography. Part I: Investigation and modeling
    J. Opt. Soc. Am. A 22, 1369-1379 (2005)
29. B. Karamata, M. Leutenegger, P. Lambelet, M. Laubscher, S. Bourquin, T. Lasser
    Multiple scattering in optical coherence tomography. Part II: Experimental and theoretical investigation of cross-talk in wide-field optical coherence tomography
    J. Opt. Soc. Am. A 22, 1380-1388 (2005)
30. A. Perentes, I. Utke, B. Dwir, M. Leutenegger, T. Lasser, P. Hoffmann, F. Baida, M. P. Bernal, M. Russey, J. Salvi, D. Van Labeke
    Fabrication of arrays of sub-wavelength nano-apertures in an optically thick gold layer on glass slides for optical studies
    Nanotech. 16, S273-S277 (2005)
31. R. Rigler, L. Edman, S. Wennmalm, M. Leutenegger, T. Anhut, T. Lasser
    Non equilibrium catalysis of single enzyme molecules
    Abstracts Pap. Am. Chem. Soc. 228, U201-U202 7-PHYS Part 2 (2004)
32. A. Perentes, A. H. Bachmann, M. Leutenegger, I. Utke, C. Sandu, P. Hoffmann
    Focused electron beam induced deposition of a periodic transparent nano-optic pattern
    Microel. Eng. 73-74, 412-416 sp. iss. SI (2004)

Book chapters

1. M. Geissbuehler, T. Spielmann, A. Formey, I. Märki, M. Leutenegger, B. Hinz, K. Johnsson, D. Van De Ville, T. Lasser
   Triplet Imaging of Oxygen Consumption During the Contraction of a Single Smooth Muscle Cell (A7r5) in
   M. Wolf, H. U. Bucher, M. Rudin, S. Van Huffel, U. Wolf, D. F. Bruley, D. K. Harrison (eds.)
   "Oxygen Transport to Tissue XXXIII"
   Adv. Exp. Med. Biol. 737#5, 263-268 (2012)
2. M. Leutenegger, K. Hassler, P. Rigler, A. Bilenca, T. Lasser
   Single Molecule Detection at Surfaces: Dual-Color Fluorescence Fluctuation Spectroscopy with Total Internal Reflection Excitation in
   K. Kneipp, American Chemical Society, R. Aroca, H. Kneipp, E. Wentrup-Byrne (eds.)
   "New Approaches in Biomedical Spectroscopy"
   Am. Chem. Soc. Symp. Ser. 963, 259-279, ISBN 0841274371 (2007)

Patents

1. T. Lasser, D. van de Ville, E. Martin-Williams, M. Leutenegger, I. Märki, M. Friedrich, M. Villiger
   Functional optical coherent imaging
   WO2010004365, EP2309919, US2011169978 (10 Jul 2008)
2. C. Hauger, W. Nahm, T. Lasser, M. Leutenegger, E. J. Martin-Williams, A. Lopez
   System and method for examining an object
   WO2009046985, DE102007048362, US2011090325 (9 Oct 2007)
3. C. Hauger, W. Nahm, T. Lasser, M. Leutenegger, E. Martin-Williams, A. Lopez
   Method and apparatus for displaying a field of a brain of a patient and navigation system for brain surgery
   EP1982645, US2009054788, US2010130869, DE102008051950 (19 Apr 2007)

Conference contributions

1. M. Leutenegger (invited)
   Super-resolved optical fluctuation imaging in three dimensions
   Laser Applications in Life Sciences LALS 2014, Ulm, Germany (29 Jun-2 Jul 2014).
2. T. Lasser, A. Bouwens, T. Bolmont, D. Szlag, C. Berclaz, S. Broillet, S. Coquoz, P. Marchand, M. Sison, J. Extermann, M. Leutenegger
   Optical Coherence Microscopy: From Tissue to Cell
   Biomedical Optics, Miami, Florida USA (26-30 Apr 2014)
3. M. Leutenegger (invited)
   Super-resolved fluorescence imaging and spectroscopy in the evanescent field
   Evanescence 2013, Université Paris Descartes, France (3-4 Oct 2013).
4. M. Leutenegger, S. Broillet, S. Geissbuehler, A. Sato, C. Pache, A. Bouwens, D. Szlag, T. Lasser
   Optical Coherence Correlation Spectroscopy (OCCS)
   Focus on Microscopy - Phase: Optical Coherence, Maastricht, The Netherlands (24-27 Mar 2013)
5. M. Leutenegger, S. Geissbuehler, N. L. Bocchio, C. Berclaz, T. Lasser
   Three-dimensional Super-resolution Optical Fluctuation Imaging
   Focus on Microscopy - Superresolution Microscopy III: Pointillism, Image Processing, Maastricht, The Netherlands (24-27 Mar 2013)
6. S. Broillet, S. Geissbuehler, A. Sato, C. Pache, A. Bouwens, D. P. Szlag, T. Lasser, M. Leutenegger
   Optical Coherence Correlation Spectroscopy (OCCS)
   BIOS 2013: Single Molecule Spectroscopy and Superresolution Imaging VI, San Francisco, California, USA, (2-7 Feb 2013)
7. S. Broillet, S. Geissbuehler, A. Sato, C. Pache, A. Bouwens, D. P. Szlag, T. Lasser, M. Leutenegger
   Optical Coherence Correlation Spectroscopy (OCCS)
   18^th International Workshop on "Single Molecule Spectroscopy and Ultrasensitive Analysis in the Life Sciences", Berlin-Adlershof, Germany (5-7 Sep 2012)
8. S. Geissbuehler, N. L. Bocchio, C. Dellagiacoma, C. Berclaz, M. Leutenegger, T. Lasser
   Balanced super-resolution optical fluctuation imaging
   18^th International Workshop on "Single Molecule Spectroscopy and Ultrasensitive Analysis in the Life Sciences", Berlin-Adlershof, Germany (5-7 Sep 2012)
9. M. Leutenegger, P. Harbi, T. Thacher, W. Raffoul, T. Lasser
   Real-time full field Laser Doppler Imaging
   10^th International Conference on Vibration Measurements by Laser and Noncontact Techniques, Ancona, Italy (26-29 Jun 2012)
10. M. Leutenegger, T. Grotjohann, I. Testa, H. Bock, N. T. Urban, F. Lavoie-Cardinal, K. I. Willig, C. Eggeling, S. Jakobs, S. W. Hell
    RESOLFT imaging and writing with a photochromic GFP
    Focus on Microscopy - Super-resolution I: STED methods, Singapore, Singapore (1-4 Apr 2012)
11. S. Geissbuehler, N. L. Bocchio, C. Dellagiacoma, C. Berclaz, M. Leutenegger, T. Lasser
    Balanced super-resolution optical fluctuation imaging
    Focus on Microscopy - Super-resolution IV: techniques, Singapore, Singapore, (1-4 Apr 2012)
12. T. Lasser, M. Villiger, C. Pache, A. Bouwens, C. Berclaz, D. Szlag, M. Leutenegger, T. Bolmont
    Optical coherence microscopy from tissue to cell
    Focus on Microscopy - OCT, ultrafast lasers, Singapore, Singapore, (1-4 Apr 2012)
13. M. Geissbuehler, N. Bocchio, V. Shcheslavskiy, M. Leutenegger, L. Bonacina, C. Kasparian, I. Märki, J.P. Wolf, T. Lasser
    Characterization of Nanoparticles Using Non-linear Correlation Spectroscopy
    ECBO 2011 - Emerging Technologies: Models and Platforms II, Munich, Germany, (22-26 May 2011)
14. A. Sato, M. Leutenegger, S. Geissbuehler, N. Bocchio, A. Bouwens, T. Lasser
    Characterization of dynamics and photophysical processes in gold nanoparticles by correlation spectroscopy
    Focus on Microscopy - Light sources and (nano) particles, Konstanz, Germany, (17-19 Apr 2011).
15. M. Leutenegger, C. Eggeling, S. W. Hell
    Confocal TIRF-STED: total internal reflection fluorescence microscopy and spectroscopy at the nanoscale
    15^th International Workshop on "Single Molecule Spectroscopy and Ultrasensitive Analysis in the Life Sciences", Berlin-Adlershof, Germany (15-18 Sep 2009)
16. M. Leutenegger, C. Eggeling, S. W. Hell
    Fluorescence microscopy and fluorescence spectroscopy at the nano-scale
    Netzwerktagung der Alexander von Humboldt-Stiftung, Münster, Germany (18–21 Nov 2008)
17. T. Lasser, D. Van de Ville, E. J. Martin-Williams, M. Leutenegger, R. A. Leitgeb, A. Lopez, M. Unser, A. Szelenyi, E. Hattingen, R. Gerlach, V. Seifert, C. Hauger, A. Raabe
    Laser Doppler Imaging Opens New Perspectives for Intra-Operative Brain Mapping
    USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland (6-7 Feb 2008)
18. I. Märki, M. Leutenegger, M. Geissbuehler, R. Robelek, E.K. Sinner, T. Lasser
    Imaging of G protein-coupled receptors in solid-supported planar membranes at the single molecule level
    USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland (6-7 Feb 2008)
19. M. Leutenegger, M. Geissbuehler, I. Märki, R. A. Leitgeb, T. Lasser
    Fast focus field calculations
    USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland (6-7 Feb 2008)
20. I. Märki, M. Leutenegger, M. Geissbuehler, R. Robelek, E.K. Sinner, T. Lasser
    Imaging of G protein-coupled receptors in solid-supported planar membranes at the single molecule level
    Proc. SPIE 6862, X8620 (19-24 Jan 2008)
21. M. Leutenegger, M. Geissbuehler, I. Märki, R. A. Leitgeb, T. Lasser
    Fast focus field calculations
    Proc. SPIE 6861, R8610 (21-24 Jan 2008)
22. M. Geissbuehler, T. Spielmann, R. Vulliamy, M. Leutenegger, I. Märki, T. Sandén, G. Persson, B. Hinz, J. Widengren, T. Lasser
    Triplet state imaging (TRIC) by modulated excitation
    Proc. SPIE 6861-23 (19-24 Jan 2008)
23. M. Leutenegger, R. Robelek, I. Märki, M. Geissbuehler, E.K. Sinner, T. Lasser
    Single molecule imaging of odorant receptors in tethered lipid membranes
    13^th International Workshop on "Single Molecule Spectroscopy and Ultrasensitive Analysis in the Life Sciences", Berlin-Adlershof, Germany (19-21 Sep 2007)
24. M. Leutenegger, M. Geissbuehler, I. Märki, R. Robelek, E.K. Sinner, T. Lasser
    Single molecule imaging of odorant receptors in supported planar lipid membranes
    EPFL BiOp inauguration symposium, Lausanne, Switzerland (5-6 Sep 2007)
25. M. Geissbuehler, M. Leutenegger, I. Märki, R. Rigler, T. Lasser, A. Bilenca
    Single molecule detection at surfaces
    Latsis Symposium 2007 on "Optical Trapping for Molecular Interactions", Lausanne, Switzerland (25-27 Jun 2007)
26. M. Leutenegger, M. Geissbuehler, I. Märki, R. Robelek, E.K. Sinner, T. Lasser
    Single molecule imaging of odorant receptors in supported planar lipid membranes
    Nanoscale Engineering of the Biointerface, Playa del Aro, Spain (28 May-1 Jun 2007)
27. M. Villiger, A. H. Bachmann, M. Leutenegger, L. Steinmann, T. Lasser, R. A. Leitgeb
    Fourier Domain Optical Coherence Microscopy with extended depth of field
    Nanoscale Engineering of the Biointerface, Playa del Aro, Spain (28 May-1 Jun 2007)
28. M. Geissbuehler, M. Leutenegger, I. Märki, H. Blom, C. Eggeling, T. Lasser
    Two color fluorescence correlation spectroscopy (FCS) and total internal reflection FCS
    Nanoscale Engineering of the Biointerface, Playa del Aro, Spain (28 May-1 Jun 2007)
29. M. Leutenegger, R. Robelek, E.K. Sinner, T. Lasser
    Single molecule imaging of odorant receptors in supported planar lipid membranes
    CHUV Research day 2007, Lausanne, Switzerland (1 Feb 2007)
30. R. Robelek, M. Leutenegger, E.K. Sinner, T. Lasser
    Single molecule imaging of odorant receptors in supported planar lipid membranes
    Winterschool, Klosters, Switzerland (14 Jan 2007)
31. T. Lasser, M. Leutenegger, V. Shcheslavskiy, I. Märki, K. Hassler, P. Rigler, A. Bilenca, E.K. Sinner, R. Robelek
    Single Molecule Detection at Surfaces
    9. Carl Zeiss sponsored workshop on FCS and related methods, Stockholm, Sweden (4-6 Dec 2006)
32. M. Leutenegger, R. Robelek, E.K. Sinner, T. Lasser
    Single molecule imaging of odorant receptors in supported planar lipid membranes
    EPFL Photonics day 2006, Lausanne, Switzerland (24 Nov 2006)
33. H. Blom, M. Leutenegger, C. Eggeling, J. Widengren, T. Lasser
    Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy
    Northern Optics 2006, Bergen, Norway (14-16 Jun 2006)
34. M. Leutenegger, H. Blom, J. Widengren, C. Eggeling, M. Gösch, T. Lasser
    Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy
    EOS Topical Meeting on Molecular Plasmonic Devices, Engelberg, Switzerland (27-29 Apr 2006)
35. M. Leutenegger, H. Blom, J. Widengren, C. Eggeling, M. Gösch, T. Lasser
    Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy
    8. annual Linz Winter Workshop, Linz, Austria (3-6 Feb 2006)
36. R. A. Leitgeb, L. Steinmann, C. Imboden, M. Villiger, M. Leutenegger, A. H. Bachmann, T. Lasser
    High-resolution Fourier domain optical coherence microscopy
    Proc. SPIE 6079-33 (Jan 2006)
37. R. A. Leitgeb, L. Steinmann, C. Imboden, M. Villiger, M. Leutenegger, A. H. Bachmann, T. Lasser
    Highly confined depth focus for Fourier domain optical coherence microscopy
    Proc. SPIE 6090-07 (Jan 2006)
38. M. Leutenegger, A. Perentes, M. Gösch, T. Lasser, P. Hoffmann
    Fluorescence Correlation Spectroscopy on a Single Aperture
    2005 Annual Meeting of the Swiss Society for Biomedical Engineering, Lausanne (28 Sep 2005)
39. B. Karamata, P. Lambelet, M. Leutenegger, M. Laubscher, S. Bourquin, T. Lasser
    A semi-analytical model accounting for multiple scattering in optical coherence tomography
    Proc. SPIE 5690, 386-396 (23 Jan 2005)
40. R. Rigler, L. Edman, S. Wennmalm, M. Leutenegger, T. Anhut, T. Lasser
    Non equilibrium catalysis of single enzyme molecules
    Abstr. Am. Chem. Soc. 228, U201-U202 7-PHYS Part 2 (22 Aug 2004)
41. T. Lasser, T. Anhut, A. Serov, K. Hassler, R. Rao, M. Leutenegger, A. von Mühlenen, R. Chatton, P. Hoffmann, I. Utke, R. Popovic, P. A. Besse, A. Rochas, M. Gösch, R. Rigler, R. Brunner
    A look into life sciences: more than a side step from industrial inspection?
    Proc. SPIE 5144, 504-512 (May 2003)